Unlocking the Power of Proteomics with SPOC

Unlocking the Power of Proteomics with SPOC

SPOC Proteomics is Set to Revolutionize Proteomics with High Plex Protein Biosensor Platform

SPOC Proteomics is Set to Revolutionize Proteomics with High Plex Protein Biosensor Platform

SPOC Proteomics is pioneering a new era of proteomics with its innovative sensor-integrated proteome-on-chip (SPOC) technology. By offering unparalleled speed, scale, and data depth, SPOC is set to accelerate drug discovery, biomarker identification, and diagnostics.

SPOC Proteomics is pioneering a new era of proteomics with its innovative sensor-integrated proteome-on-chip (SPOC) technology. By offering unparalleled speed, scale, and data depth, SPOC is set to accelerate drug discovery, biomarker identification, and diagnostics.

About SPOC Proteomics

About SPOC Proteomics

SPOC Proteomics is a deep-tech life sciences startup that has developed a transformative new proteomic biosensor platform termed sensor-integrated proteome-on-chip (SPOC). SPOC Proteomics offers the world’s first and only platform that provides simultaneous quantitative, qualitative, and kinetic data in a single assay at scale, to support drug and vaccine development, protein biomarker discovery, and diagnostics.

SPOC Proteomics is a deep-tech life sciences startup that has developed a transformative new proteomic biosensor platform termed sensor-integrated proteome-on-chip (SPOC). SPOC Proteomics offers the world’s first and only platform that provides simultaneous quantitative, qualitative, and kinetic data in a single assay at scale, to support drug and vaccine development, protein biomarker discovery, and diagnostics.

7201 E Henkel Way Suite 285 Scottsdale, AZ 85255

7201 E Henkel Way Suite 285 Scottsdale, AZ 85255

About SPOC Proteomics

+2,400

+2,400

full-length folded proteins on 1.5 SQ-CM Biosensor Chip

full-length folded proteins on 1.5 SQ-CM Biosensor Chip

SPOC enables up to 2400 unique full-length folded proteins per single biosensor chip, for simultaneous analysis using surface plasmon resonance (SPR) and up to 10,000 protein targets per chip for mass spectrometry analysis. SPOC chip proteins are produced in ~4 hours from an array of plasmid DNA with cell-free human lysate and simultaneously captured directly onto biosensor chip surfaces.

SPOC enables up to 2400 unique full-length folded proteins per single biosensor chip, for simultaneous analysis using surface plasmon resonance (SPR) and up to 10,000 protein targets per chip for mass spectrometry analysis. SPOC chip proteins are produced in ~4 hours from an array of plasmid DNA with cell-free human lysate and simultaneously captured directly onto biosensor chip surfaces.

This unique protein production method circumvents challenges and expense of traditional recombinant protein workflows, reducing costs 10-100x and substantially decreasing production time. Our mission is to utilize SPOC to democratize high-throughput kinetic proteomic screens and facilitate early disease detection – ultimately enabling disease preemption.

This unique protein production method circumvents challenges and expense of traditional recombinant protein workflows, reducing costs 10-100x and substantially decreasing production time. Our mission is to utilize SPOC to democratize high-throughput kinetic proteomic screens and facilitate early disease detection – ultimately enabling disease preemption.

Meet our leadership team

Meet our leadership team

SPOC Proteomics is pioneering a new era of proteomics with its innovative sensor-integrated proteome-on-chip (SPOC) technology. By offering unparalleled speed, scale, and data depth, SPOC is set to accelerate drug discovery, biomarker identification, and diagnostics.

SPOC Proteomics is pioneering a new era of proteomics with its innovative sensor-integrated proteome-on-chip (SPOC) technology. By offering unparalleled speed, scale, and data depth, SPOC is set to accelerate drug discovery, biomarker identification, and diagnostics.

Leadership

Leadership

Bharath Takulapalli, PhD

Bharath is inventor of multiple foundational life science technologies designed to extract 1000x more information from biological systems. He conceived SPOC platform for democratizing proteomics, and FENT CMOS-nanopore technology for ultra-fast DNA sequencing. Bharath has B.Tech from IIT Madras and PhD from Arizona State University.

Founder & CEO

Mukilan Mohan, MS MBA

At SPOC, Mukil is responsible for business operations and finance, co-owns product and strategy. He previously led product management and system design functions for revops systems at TD-Ameritrade’s investor education division. Prior to that, he held multiple consulting roles in IT and management. He has an MS (EE) & an MBA from ASU

Co-Founder & COO

Dr. Lydia Gushgari

Dr. Lydia Gushgari has 10 years’ experience in immunology, virology, infectious diseases, vaccine development, melanoma, clinical laboratory diagnostic immunology, and autoimmunity. Lydia completed her Doctoral studies at Arizona State University, studying plant-produced vaccines and attenuated viral vaccine vectors for HIV.

Director of Clinical Research & Chief of Staff

Bharath Takulapalli, PhD

Founder & CEO

Bharath is inventor of multiple foundational life science technologies designed to extract 1000x more information from biological systems. He conceived SPOC platform for democratizing proteomics, and FENT CMOS-nanopore technology for ultra-fast DNA sequencing. Bharath has B.Tech from IIT Madras and PhD from Arizona State University.

Mukilan Mohan, MS MBA

Co-Founder & COO

At SPOC, Mukil is responsible for business operations and finance, co-owns product and strategy. He previously led product management and system design functions for revops systems at TD-Ameritrade’s investor education division. Prior to that, he held multiple consulting roles in IT and management. He has an MS (EE) & an MBA from ASU

Dr. Lydia Gushgari

Director of Clinical Research & Chief of Staff

Dr. Lydia Gushgari has 10 years’ experience in immunology, virology, infectious diseases, vaccine development, melanoma, clinical laboratory diagnostic immunology, and autoimmunity. Lydia completed her Doctoral studies at Arizona State University, studying plant-produced vaccines and attenuated viral vaccine vectors for HIV.

Bharath Takulapalli, PhD

Founder & CEO

Bharath is inventor of multiple foundational life science technologies designed to extract 1000x more information from biological systems. He conceived SPOC platform for democratizing proteomics, and FENT CMOS-nanopore technology for ultra-fast DNA sequencing. Bharath has B.Tech from IIT Madras and PhD from Arizona State University.

Mukilan Mohan, MS MBA

Co-Founder & COO

At SPOC, Mukil is responsible for business operations and finance, co-owns product and strategy. He previously led product management and system design functions for revops systems at TD-Ameritrade’s investor education division. Prior to that, he held multiple consulting roles in IT and management. He has an MS (EE) & an MBA from ASU

Dr. Lydia Gushgari

Director of Clinical Research & Chief of Staff

Dr. Lydia Gushgari has 10 years’ experience in immunology, virology, infectious diseases, vaccine development, melanoma, clinical laboratory diagnostic immunology, and autoimmunity. Lydia completed her Doctoral studies at Arizona State University, studying plant-produced vaccines and attenuated viral vaccine vectors for HIV.

Board of directors and Scientific Advisory Board

Dr. George Church - Professor of Genetics

Dr. George Church is professor of Genetics at Harvard Medical School and director of Personal Genome Project. His 1984 Harvard PhD included the first methods for direct genome sequencing and molecular multiplexing, which helped initiate the Human Genome Project.

Harvard Medical School

Dr. Chenming Hu – Professor of EECS

Dr. Chenming Hu, Professor Emeritus of EECS at UC Berkeley,visionary inventor of the FinFET. He is a world’s foremost authority on CMOS device physics, modeling and manufacturing. Intel began commercializing the 3D transistor based chips in 2011, with most others following soon.

University of California, Berkeley

Dr. Joshua LaBaer – Director, Center for Personalized Medicine

Dr. Joshua LaBaer is the Director of Virginia Piper center for personalized diagnostics at the Biodesign Institute ASU, home to DNASU plasmid repository and the Sequencing Core. He is a medical oncologist, cancer researcher and nation’s leading proteomics expert. 

ASU Biodesign Institute

Dr. Abhay Sanan – President, Center for Neurosciences

Dr. Abhay Sanan is a Neurosurgeon with more than 24 years of experience in broad areas of neurosciences. He is the lead investor and a member of the Board of Directors at SPOC. He understands how technology drives healthcare outcomes and invests in paradigm changing technologies.

Center for Neurosciences, Tucson

Jean Pierre Millon, MBA

JP Millon currently serves on the board of CVS Health that combines CVS Pharmacy, Caremark, Minute Clinic and CVS Specialty. He is the former President and Chief Executive Officer of PCS Health Systems Inc. He previously served on the boards of Caremark Rx and Advance PCS.

DIRECTOR

Dr. George Church - Professor of Genetics

Harvard Medical School

Dr. George Church is professor of Genetics at Harvard Medical School and director of Personal Genome Project. His 1984 Harvard PhD included the first methods for direct genome sequencing and molecular multiplexing, which helped initiate the Human Genome Project.

Dr. Chenming Hu – Professor of EECS

University of California, Berkeley

Dr. Chenming Hu, Professor Emeritus of EECS at UC Berkeley,visionary inventor of the FinFET. He is a world’s foremost authority on CMOS device physics, modeling and manufacturing. Intel began commercializing the 3D transistor based chips in 2011, with most others following soon.

Dr. Joshua LaBaer – Director, Center for Personalized Medicine

ASU Biodesign Institute

Dr. Joshua LaBaer is the Director of Virginia Piper center for personalized diagnostics at the Biodesign Institute ASU, home to DNASU plasmid repository and the Sequencing Core. He is a medical oncologist, cancer researcher and nation’s leading proteomics expert. 

Dr. Abhay Sanan – President, Center for Neurosciences

Center for Neurosciences, Tucson

Dr. Abhay Sanan is a Neurosurgeon with more than 24 years of experience in broad areas of neurosciences. He is the lead investor and a member of the Board of Directors at SPOC. He understands how technology drives healthcare outcomes and invests in paradigm changing technologies.

Jean Pierre Millon, MBA

DIRECTOR

JP Millon currently serves on the board of CVS Health that combines CVS Pharmacy, Caremark, Minute Clinic and CVS Specialty. He is the former President and Chief Executive Officer of PCS Health Systems Inc. He previously served on the boards of Caremark Rx and Advance PCS.

Dr. George Church - Professor of Genetics

Harvard Medical School

Dr. George Church is professor of Genetics at Harvard Medical School and director of Personal Genome Project. His 1984 Harvard PhD included the first methods for direct genome sequencing and molecular multiplexing, which helped initiate the Human Genome Project.

Dr. Chenming Hu – Professor of EECS

University of California, Berkeley

Dr. Chenming Hu, Professor Emeritus of EECS at UC Berkeley,visionary inventor of the FinFET. He is a world’s foremost authority on CMOS device physics, modeling and manufacturing. Intel began commercializing the 3D transistor based chips in 2011, with most others following soon.

Dr. Joshua LaBaer – Director, Center for Personalized Medicine

ASU Biodesign Institute

Dr. Joshua LaBaer is the Director of Virginia Piper center for personalized diagnostics at the Biodesign Institute ASU, home to DNASU plasmid repository and the Sequencing Core. He is a medical oncologist, cancer researcher and nation’s leading proteomics expert. 

Dr. Abhay Sanan – President, Center for Neurosciences

Center for Neurosciences, Tucson

Dr. Abhay Sanan is a Neurosurgeon with more than 24 years of experience in broad areas of neurosciences. He is the lead investor and a member of the Board of Directors at SPOC. He understands how technology drives healthcare outcomes and invests in paradigm changing technologies.

Jean Pierre Millon, MBA

DIRECTOR

JP Millon currently serves on the board of CVS Health that combines CVS Pharmacy, Caremark, Minute Clinic and CVS Specialty. He is the former President and Chief Executive Officer of PCS Health Systems Inc. He previously served on the boards of Caremark Rx and Advance PCS.

For more information on the SPOC platform, get in touch:

Contact Us

Privacy & Conditions

1600 Adams Drive Suite236

Menlo Park, CA 94025

7201 E Henkel Way, Suite 285 Scottsdale, AZ 85255

480-219-9506

All rights reserved © 2024

For more information on the SPOC platform, get in touch:

Contact Us

Privacy & Conditions

1600 Adams Drive Suite236

Menlo Park, CA 94025

7201 E Henkel Way, Suite 285 Scottsdale, AZ 85255

480-219-9506

All rights reserved © 2024

For more information on the SPOC platform, get in touch:

Contact Us

1600 Adams Drive

Suite236



Menlo Park, CA 94025

7201 E Henkel Way

Suite 285



Scottsdale, AZ 85255

480-219-9506

Privacy & Conditions

All rights reserved © 2024